The HPS4 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to HPS4, and HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. This antibody recognizes Homo Sapiens, and Human antigen. The HPS4 antibody has been validated for the following applications: EIA, Immunoassay, Precipitation, ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor(GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38(PubMed:23084991)